A packaging machine to ensure the safety and protection of your cytotoxic products in glass vials or flasks
Combiskinner Cytobloc® FB300 -AI59

Transparent glass bottles and vials: the security solution

  • A unique protection and security system for glass bottles and vials containing delicate cyto-toxic products
  • Handle multiformats with a range of glass vials from 2 ml to 100 ml
  • Reliability of the process at high speeds, even for the lightest products whose weight can be lower than 10 gr
  • Monitoring and control of product temperatures 
  • Hot air shrink technology adapted to your product specifications 

Features

A compact, multi-module packaging machine for an optimized floor space footprint
Protection solution adapted to manage glass bottles equipped with a cup at their base

Technology dedicated to the protection and security of cytotoxic products

Cytobloc® is a unique solution for protecting and securing transparent glass vials to protect personnel from contamination during handling. Composed of a cup and an anti-breakage shrink-sleeve, its implementation involves a lateral, upper and lower guidance system throughout the process.

The Multi-format flexibility of the machine allows the labelling of different containers' formats, up to 100mL vials
Extreme format flexibility from 2 ml to 100 ml

Mastery of multi-format management of extremes

This equipment is specifically designed to handle the particularly wide range of cytotoxic product containers, from 2 to 100ml, on more than 10 different formats. The tooling includes common elements and elements specific to each format. Format changes can be made without tools, and settings are pre-saved in the interface and automatically synchronized, for quick and easy operations.

A vacuum conveyor ensures that the lightest products remain in a vertical position throughout the production line
Reliability of high speed holding of extremely light products

A technology adapted to the high speed of feather weights' products

An adapted technology that allows products weighing less than 10 grams to be held upright at 300 products per minute, from the machine entrance to the shrink-sleeve application, without loss of pitch, and a confirmation system for shrink-sleeve application without loss of pitch until the shrink tunnel entrance.

A graphic interface allows to control and monitor in live the temperatures inside the Shrink tunnel
Monitoring and temperature control

The guarantee of a product at the right temperature

Different temperature sensors are installed in the shrink tunnel. The first ones are used to ensure the right shrink temperature of the shrink-sleeve and the second ones are used to measure the temperature deviation for the safety of the product. If the temperature increases, the information is transmitted to the operator for corrective action and then recorded for the traceability of the product.  Then communicate to a server located outside the machine.

A hot air Shrink Applicator with controlled power consumption
Hot air shrink tunnel with controlled consumption

Hot air shrink technology adapted to sensitive products and optimized consumption

The hot air shrink tunnel  ensures that sensitive products are not altered during the shrink-sleeve label shrinking phase. Each recipe has its own adjustment and memorized temperature for both the infra-red ramps and the hot air nozzles which ensure the finishing of each product. The settings per recipe allow to control and optimize the energy consumption for each format.

Options

Separated conveyors to avoid heat transfer and maintain product quality upstream of production
Separate conveyors to avoid altering the products

Separate conveyors to break the thermal bridge

The product transfer conveyors are dissociated, thus avoiding the transfer of calories to the products upstream of the machine and avoiding any alteration of the products during the accumulation phases at the machine entrance.

A 360° camera control module to ensure the conformity of finished products
Camera control

360° product control

A control system with 4 cameras allowing a 360° control around the product twice: after the shrink-sleeve apply and after the shrinking. This system is connected to an ejection system and a line clearance in case of anomaly.

A vertical ejection system to maintain the condition of unstable products
Ejection system for standing products at high speed

High speed upright product ejection without dropping them

The ejection module has been specially designed to discard light and unstable vials running at high speed, while keeping them in an upright position, so that they are not altered during the operation.

A line clearance module prevents products from spoiling or deterioratingon on the conveyor belt during unscheduled machine or production line stops
Line clearance module

Line clearance in case of machine stop

The line clearance module avoids any alteration of the products in case of machine stop. 
This module avoids keeping products in the shrink tunnel during a stop due to a production anomaly.

Specifications

* Non contractual information
Packaging machine with double Sleeve Label application heads and a double shrink tunnel for your sensitive pharmaceutical products

Machines

Conveyor height 980 +/- 50 mm
Speed 300 cpm
Cutting diameter 100 mm
Electrical consumption 59 KW/h
Machine length 6400 mm
Pharmaceutical product shapes that can be decorated with a secure Cytobloc shrink sleeve label and cup

Packaging

Materials Glass
Shapes Cylindrical
Product diameter 15 to 65 mm
Product height 32 to 95 mm
Sizes 2 - 100 ml

Sleeves

Applications Full body with protective cup on its base
Films OPS
Film thickness 95 microns

MARKETS & PACKAGING

Cytobloc packaging innovation, including a Shrink Sleeve Label and an anti-breakage cup
Glass vial of injectable solution with Cytobloc innovation
Cytotoxic injectable solutions
(2 ml - 100 ml)
Glass
Glass vial of injectable product
injectable product in a glass vial
Cytotoxic injectable solutions
(2 ml - 100 ml)
Glass
Packaging shape of injectable solution with tamper evidence
solution for perfusion
Injectable solutions
(2 ml - 100 ml)
Glass
Cytobloc packaging innovation, including a Shrink Sleeve Label and an anti-breakage cup
Glass vial of injectable solution with Cytobloc innovation
Cytotoxic injectable solutions
(2 ml - 100 ml)
Glass
Glass vial of injectable product
injectable product in a glass vial
Cytotoxic injectable solutions
(2 ml - 100 ml)
Glass
Packaging shape of injectable solution with tamper evidence
solution for perfusion
Injectable solutions
(2 ml - 100 ml)
Glass
Cytobloc packaging innovation, including a Shrink Sleeve Label and an anti-breakage cup
Glass vial of injectable solution with Cytobloc innovation
Cytotoxic injectable solutions
(2 ml - 100 ml)
Glass
Glass vial of injectable product
injectable product in a glass vial
Cytotoxic injectable solutions
(2 ml - 100 ml)
Glass
Packaging shape of injectable solution with tamper evidence
solution for perfusion
Injectable solutions
(2 ml - 100 ml)
Glass